Images of a representative animal from each of the CD38-S3I-NP, S3I-NP, and PBS groups are shown in Figure 4A. Animals in the CD38-S3I-NP group had significantly lower tumor volume compared to the S3I-NP group at 240 and 288 h (p = 0.018 and p = 0.006, respectively). The gene discussed is CD38; the disease is neoplasm.