EIF2AK2 and glioblastoma: The ability of VP35 to target PKR seems to be cell- and species-specific, as MARV VP35 can inhibit PKR activation in 293T cells but not in human glioblastoma U-251-MG cells, or in a cell line derived from Rousettus bats (Rousettus aegyptiacus) [28], a reservoir of MARV [29].