Therefore, treatment with AZA was associated with an increase in KCNMA1 expression in some colon cancer cell lines (i.e., SW620, SKCO1, COLO205, and SW480) (Figure 8c ), while a lack of effect, or even a downregulation of KCNMA1, was instead observed for other cells lines, such as LOVO and COLO320 (Figure 8c). Here, KCNMA1 is linked to malignant colon neoplasm.