PRDX4 and cancer: Among the genes located in the X chromosome that appear to be implicated in cancer (i.e., VEGFD, PRDX4, ZBTB33, PASD1), the 1 that mainly could be correlated with NB is L1CAM, since it plays a role in axon outgrowth and fasciculation, neuronal migration, and survival, synaptic plasticity, and regeneration after trauma [30].