RYR1 and myopathy: The presence of mild weakness in patients originally referred for the investigation of MH suggests that some of these patients may in fact have had a mild RYR1-related myopathy, in cases where cores were present even fulfilling the criteria for either Central Core Disease (CCD) or Multi-minicore Disease (MmD); this is an important observation emphasizing that MH patients could benefit from a formal assessment by a neurologist with experience in neuromuscular disorders, something which is currently not performed as a standard at all MH centres.