We did not confirm any significant differences among studied genotypes regarding such parameters as sex, age of MM onset, ISS stage, cytogenetic changes, type of MM (secretory-, non-secretory MM, light chain disease), monoclonal protein class (IgG, IgA, etc.), light chain type (kappa, lambda), loss of body weight before treatment, baseline hemoglobin concentration, estimated glomerular filtration rate, the presence of renal insufficiency at diagnosis of MM, levels of albumin, β2-microglobulin, calcium, creatinine, and C-reactive protein. This evidence concerns the gene CRP and Renal insufficiency.