Interestingly, as there is a functional link between α4β1 and the histone methyltransferase G9a, which regulates migration of Jurkat (T-ALL) cells (214), the G9a inhibitor CM-272 has been reported to block cell proliferation and infiltration in an in vivo xenograft model (215). The gene discussed is EHMT2; the disease is acute lymphoblastic leukemia.