In one of the Rheumavax studies, GM-CSF+IL-4 culture medium was supplemented with the NF-κB inhibitor Bay 11-7082 and then the cells were exposed to citrullinated peptides of aggrecan, vimentin, collagen type II and Aα and Bβ fibrinogen, which are putative RA autoantigens (59). This evidence concerns the gene NFKB1 and rheumatoid arthritis.