Immunohistochemistry analysis of the xenotransplants obtained in mice after injection of OMCs treated with different cancer sera revealed that the immunohistochemistry patterns of malignant differentiation in BRCA1-mutated fibroblasts and PTEN-deficient MCF10A cells were always identical regardless of the cancer sera type that the cells were exposed to, confirming that horizontal transfer of malignant traits is a concept applicable also to epithelial cells (MCF10A) with a different oncosuppressor mutations (PTEN) than the ones previously investigated (BRCA1, P16 and P53)19,20,25. The gene discussed is PTEN; the disease is cancer.