GSDMB and asthma: The ORMDL3/GSDMB region is strongly associated with childhood onset asthma13,34, and to rule out that the weaker associations in high African ancestry populations may be due to the inclusion of adult onset asthmatics in some of the CAAPA studies, we re-tested the association between the 22 candidate SNPs and asthma, using only those studies where age of onset was available, or that were pediatric studies.