Melanomas were observed in the UVB-exposed Tyr-Cre-BRAFCA/Tg-ZDHHC13/MC1RR151C mice, with the Tyr-Cre-BRAFCA/Tg-ZDHHC13 mice and Tyr-Cre-BRAFCA/Tg-MC1RR151C mice serving as controls. This evidence concerns the gene ZDHHC13 and melanoma.