USP7 and urinary bladder cancer: In order to evaluate if the pharmacological inhibition of USP7 through P5091, by increasing the turnover of the CCDC6 protein, could influence the half-life of CCDC6, J82, T24, 5637 and KU-19-19 bladder cancer cells were treated with P5091 for 4 h, or with DMSO as a control, and then exposed to cycloheximide (CHX), to block new protein synthesis, at the indicated times.