This could be explained by the absence (or reduction) of peak action of these analogs due to their stabler profile and smaller glycemic variability.45, 60 Nevertheless, the present systematic review revealed that insulin analogs did not seem to cause less maternal hypoglycemia compared with human insulins, which is in line with the findings of Siebenhofer et al (2006).61 Here, INS is linked to Hypoglycemia.