Of specific interest is the observation that these miRNAs are also found to be elevated in serum and plasma of patients with malignant (T)GCT compared to healthy individuals, and as such being considered as a promising alternative serum biomarker for diagnosis of (T)GCT in addition to alpha‐fetoprotein (AFP) and human chorionic gonadotropin (hCG) (Gillis et al., 2013; Ruf et al., 2014; Syring et al., 2015; van Agthoven et al., 2017; Dieckmann et al., 2017; Terbuch et al., 2018; Mego et al., 2019). This evidence concerns the gene AFP and granular cell tumor.