OXTR and eating disorder: Oxytocin has anorexigenic actions.130, 146, 159, 160 Oxytocin administration has been shown to reduce food intake in laboratory animals and humans.161, 162, 163 The anorexigenic effect of oxytocin has been shown to be stronger in diet‐induced obese rodents.164 However, a meta‐analysis revealed that the anorexigenic effect of oxytocin administration is not statistically significant in humans.161 SNPs of the gene encoding the oxytocin receptor have been shown to be associated with eating disorders including anorexia nervosa and bulimia nervosa.165