OXT and major depressive disorder: In summary, oxytocin in rodents has been shown to reduce anxiety‐related behaviours via acting on the medial prefrontal cortex, hypothalamic paraventricular nucleus, central amygdala and raphe nucleus; to attenuate depression‐like behaviour by acting on the nucleus accumbens; and to reduce neuroendocrine stress responses by acting on the hypothalamic paraventricular nucleus.