CAV3 and persistent truncus arteriosus: However, there was no significant difference in absolute ICa amplitude at the surface membrane of sham and TAC Cav‐3 OE myocytes (Figure 4C), so that the increase in cell size (and thus capacitance) following TAC resulted in a significant decrease in ICa density at the cell surface (Figure 4d); this contrasts with the small increase in absolute ICa at the surface membrane of WT myocytes following TAC, so that ICa density at the surface membrane is unaltered following TAC in these cells (Figure 4c,d).