Knockout and loss‐of‐function mutations of Cav‐3 are associated with hypertrophic cardiomyopathy, further supporting a role for Cav‐3 as an inhibitor of cardiac hypertrophic signalling pathways (Hayashi et al., 2004; Woodman et al., 2002). The gene discussed is CAV3; the disease is hypertrophic cardiomyopathy.