The JAK-STAT signaling pathway can be induced by a number of cytokines19 (such as Interleukin family) and cell growth factors20 (such as epidermal growth factor and fibrogenic growth factor), all of whichcan play a specific and effective biological function in cell proliferation,differentiation or apoptosis, immune function regulation and tumor formation.21 This evidence concerns the gene SOAT1 and neoplasm.