To investigate the inflammatory response of the LPS induced sepsis rat to LBPtreatment, inflammatory cytokines (IL-1β, IL-6, IL-8, TNF-α and NF-κB) weredetermined in kidney cortex homogenates after 12h treatment through theEnzyme-Linked Immunosorbent Assay (ELISA). The gene discussed is CXCL8; the disease is Sepsis.