CIAO3 and pertussis: The responses to DTaP-IPV co-administered with MMR-RIT were non-inferior to co-administration with MMR II in terms of BRRs to diphtheria, tetanus, and pertussis antigens at D42, as the lower limit of the 97.5% CIs of the difference in BRR (MMR-RIT minus MMR II) was ≥-10% (predefined threshold) for anti-diphtheria toxoid (DT), anti-tetanus toxoid (TT), anti-pertussis toxoid (PT), anti-filamentous hemagglutinin (FHA), and anti-pertactin (PRN) antibodies (Table 4).