On the other hand, other genes have mutations identified in more than one related disorders, such as PTPN11 for both NS and NSML (Pandit et al., 2007; Roberts et al., 2007; Tartaglia et al., 2010), and KRAS for NS and CFC (Aoki & Matsubara, 2013), MAP2K1 and SOS1 for CFC and NS (Kouz et al., 2016). The gene discussed is KRAS; the disease is cardiofaciocutaneous syndrome.