MAP3K12 and neoplasm: miRNAs can also impede biosynthesis of specific proteins, and subsequently regulate multiple physiological processes.5, 6 Also, accumulating evidence shows that dysregulation of miRNAs can have tumor‐suppressive or oncogenic effects in the development and progression of several cancers, including prostate cancer, by regulating tumor growth, metastasis, and epithelial to mesenchymal transition (EMT).7, 8, 9 It has been reported that miR‐133a and miR‐150 inhibit the growth of metastatic prostate cancer by regulating MAP3K12 expression or by activating PI3K/AKT signaling.