RARRES2 and liver dysplastic nodule: Many lines of evidence, ranging from in vitro experiments to epidemiological studies, have demonstrated that inflammation also plays a crucial role in the pathogenesis and progression of DN.18 Currently, some management targeting cytokines such as MCP‐1 have shown a promising effect in reducing urinary protein in DN.19 In this study, we found that chemerin could induce inflammation and cause endothelial injury in DN through its receptor ChemR23.