Although our results suggest a low toxicity of JPH203 towards normal cells, it is important to mention that the impairment of the transport of branched‐chain amino acids at the blood‐brain barrier caused by a LAT1 deficiency has also been described to cause autism spectrum disorders in mice.33 Hence, JPH203 could lead to psycho‐cognitive disorders in patients. The gene discussed is SLC7A5; the disease is Cognitive impairment.