EGFR and non-small cell lung carcinoma: This is an important option for physicians and is recognized in current treatment guidelines (Novello et al. 2016), as it appears to reduce the risk of ‘disease flare’ (sudden increases in tumor growth and disease-related symptoms) in EGFR mutation-positive NSCLC patients with slow progressive disease (PD) (Chaft et al. 2011; Riely et al. 2007; Yap et al. 2017).