Similar to our observations, among cases with miscarriage history and/or MeS, ApoA1, HP, TF, fibrinogen, and TTR have also been reported in independent studies in humans or mouse models (Rangel-Zúñiga et al., 2015; Geyer et al., 2016; Hsieh et al., 2016). Here, APOA1 is linked to spontaneous abortion.