In the current study, we addressed the regulation of transcription and protein expression of several pro-inflammatory cytokines (IL-1β, IL-6, and IL-8) by CBD, ATMi and γ-irradiation, alone or in combinations, in U87MG GBM cells (Figure 8) that could be critically important for in vivo conditions. The gene discussed is CXCL8; the disease is glioblastoma.