Partial but significant suppression of JNK1/2 phosphorylation in the presence of KU60019 (1-2 μM) further decreased activation of JNK downstream targets, cJUN-P(S73) and ATF2-P(T71), in CBD-treated non-irradiated or irradiated GBM cells 4 h after treatment (Figure 1B). This evidence concerns the gene MAPK8 and glioblastoma.