In the TCGA ccRCC cohort, APLNR mRNA expression levels were negatively correlated with histological grade (Pearson’s r = −0.22, p = 5.2e−07) and pT-stage of the tumour (Pearson’s r = −0.23, p = 2.7e−07). This evidence concerns the gene APLNR and nonpapillary renal cell carcinoma.