With regard to the surface expression of CD39 in the CD3+ CD4+ CD25high CD127low FoxP3+ CD39+ subset, it significantly correlated with IFNγ and IL-17A levels, and with the MFI of TNF in CD4+ TNF+ cells in both patients and controls, and also with the MFI of IFNγ in CD4+ IFNγ+ cells and the frequency of CD4+ IL-17A+ cells only in MS patients (Table 2). This evidence concerns the gene ENTPD1 and myeloid sarcoma.