In the early acute and acute phases of FV infection, the majority of infected MΦs in bone marrow were identified as bone marrow MΦs (CD68+ CD11blow F4-80high MHC IIint CD115int CD169+); in the late phase of infection, the population of MΦs in bone marrow contracted and was comprised of only low numbers of bone marrow MΦs and metallophilic MΦs (CD68+ CD11b+ F4-80− CD169+). This evidence concerns the gene ITGAM and infection.