In addition, we selected a normal pancreatic ductal epithelial cell (HPDE6.C7) and a panel of pancreatic cancer cell lines (AsPC1, BxPC3, Capan1, Capan2, CFPAC1, HPAF II, MIAPaca2, Panc1, Panc03.27, PSN1, PL45, SW1990, Hs766T) to detect the mRNA level of FOXM1 and the IC50 for gemcitabine, and analyzed the correlation between the two. This evidence concerns the gene FOXM1 and familial pancreatic carcinoma.