MCM3AP and hepatocellular carcinoma: Moreover, based on two other GEO datasets (GSE45436 and GSE54236) from R2: Genomics Analysis and Visualization Platform (http://r2.amc.nl), we found that MCM3AP-AS1 expression was prominently higher in HCC tissues compared to normal liver tissues (P < 0.0001, Fig. 1c and d).