In our previous study, we find that lncRNA TUSC7 is down-regulated in HCC and indicates poor prognosis of patients, and it inhibits EMT and HCC metastasis by acting as miR-10a sponge and subsequently leads to Eph tyrosine kinase receptor A4 (EphA4) upregulation [25]. This evidence concerns the gene EPHA4 and hepatocellular carcinoma.