She was noted to have oedematous swelling of the cheeks, eyelids and lips, and coexistent skin lesions, liver damage, pancytopenia with white blood cell (WBC) count of 1.90 × 109/L, hypofibrinogenemia, plasma EBV-DNA 3.26 × 103copies/L, EBV-DNA in peripheral blood mononuclear cells (PBMCs) of 5.93 × 104 copies/L, ferritin 1090.7 μg/L, interleukin-6 (IL-6) level of 74.45 pg/mL and soluble interleukin-2 receptor (sIL-2R) level of 2083 U/mL. The gene discussed is IL6; the disease is Hypofibrinogenemia.