ATG5 and neoplasm: Although, as shown previously [10], oncogenic RAS-expressing atg5−/- or atg7−/- cells display reduced tumor growth, we found that CDH1 expression was largely reduced in oncogenic RAS-expressing atg7−/- or atg5−/- tumors compared to oncogenic RAS-expressing Atg7+/+ or Atg5+/+ tumors (Figure 1(c); Figure S1(c)).