MALAT1 and breast cancer: Moreover, the results from TEAD reporter assays, co-IP, qPCR, ChIP-qPCR, and functional rescue experiments demonstrated that MALAT1 lncRNA sequesters the transcription factor TEAD, thereby blocking TEAD from associating with its co-activator YAP and target genes, which in turn leads to inhibition of TEAD’s transcriptional activity and pro-metastatic function in breast cancer [29] (Figure 2c).