NFKB1 and familial pancreatic carcinoma: In our earlier studies on the anticancer property of garcinol, we demonstrated modulation of NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) signaling by garcinol, leading to induction of apoptosis in receptor positive and triple negative breast cancer cells [2], as well as prostate and pancreatic cancer cells [3].