High tissue expression levels of miRNA-151a-5p have been correlated with intrahepatic metastasis, cell migration, and invasion [25], while FAK (the focal adhesion kinase gene that is the host gene of miRNA-151a-5p) is usually co-expressed with miRNA-151a-5p, and it has been suggested that the two function synergistically to enhance HCC cell motility [25]. This evidence concerns the gene PTK2 and hepatocellular carcinoma.