Tumor suppressive lncRNAs (GAS5, MEG3, FER1L4 and LINC00672) and oncogenic lncRNAs (CCAT2, BANCR, NEAT1, MALAT1, H19 and Linc-RoR) have been identified as key regulators of the established tumor suppressor or oncogenic pathways in EC (Figure 1). The gene discussed is GAS5; the disease is neoplasm.