Most of the chemokines and cytokines were significantly upregulated after ZIKV infection, including CXCL10, CCL5, CCL7, CCL2, CXCL1, CCL12, CXCL9, CXCL2, CCL4, CXCL11, CXCL13, CCL11, CXCL5, IL6, IL7, PTGS2, and LIF. The gene discussed is CXCL9; the disease is Zika virus infectious disease.