The second, KIF5A variant c.1402C>T (p.Arg468Trp), which altered the stalk part of the protein, was identified in a female proband with pyramidal signs, ataxia, dysdiachokinesia, bradykinesia, titubation, ophthalmoparesis and dementia, in whom first symptoms appeared after turning 40. This evidence concerns the gene KIF5A and cerebellar ataxia.