Mutations in DJ-1, a mitochondrial peroxiredoxin-like peroxidase that plays a role in scavenging mitochondrial ROS, cause an autosomal recessive form of PD (Bonifati et al., 2003; Ammal Kaidery and Thomas, 2018), indicating a contribution of ROS in PD pathogenesis. The gene discussed is PARK7; the disease is Parkinson disease.