SPINT1 and carcinoma: For those epithelial/carcinoma lines expressing matriptase, 382 out of the 391 lines (98%) express both HAI-1 and HAI-2 together (Figure 1(B)), consistent with our previous study in which all 21 matriptase-expressing epithelial/carcinoma lines express both HAI-1 and HAI-2 at protein levels.19