A mutation in cct2 has been found in a family with Leber congenital ameurosis retinal phenotype (Minegishi et al., 2016; Minegishi et al., 2018) and mutations in cct4 and cct5 have been related to sensory neuropathy (Pereira et al., 2017; Lee et al., 2003; Hsu et al., 2004; Bouhouche et al., 2006). Here, CCT4 is linked to Sensory neuropathy.