All depends on the type of cancer, the receptors, the age of patients, [...] if you say a woman with 80 years-old with a conserving surgery, has receptors highly positive, it is a small tumour, early stage, or doesn’t have risk factors, we can go with conserving surgery, radiotherapy and hormone therapy, yes, we can do [..] But if you have positive hormonal receptors with a HER-2+++, is totally different (02, female, public sector). The gene discussed is NR4A1; the disease is neoplasm.