Based on KEGG annotation, 18 pathways were identified, many of which were cancer-related, such as the p53 signaling pathway, pathways in cancer, PI3K-Akt signaling pathway, small cell lung cancer, chronic myeloid leukemia and cell cycle (Fig. 7b). This evidence concerns the gene AKT1 and chronic myelogenous leukemia, BCR-ABL1 positive.