As expected, patients with high CAC (> 100 AUs) were older, higher prevalence of clinical CVD and diabetes, had higher levels of systolic BP, hsCRP, TNF, IL-6 and, lower levels of triglycerides, creatinine, serum albumin, total testosterone in male,and T-score of tBMD (Table 1). The gene discussed is IL6; the disease is diabetes mellitus.