SFRP2 and Miyoshi myopathy: A number of molecules have been implicated in the suppression of OB differentiation in MM including the wingless-related integration site (Wnt)-signalling inhibitor Dickkopf-related protein 1 (Dkk1) [7,8], secreted frizzled-related protein 2 (sFRP-2) [9,10], interleukin 7 (IL-7) [11,12] and hepatocyte growth factor (HGF) [11], IL-3 [13,14] and sclerostin (SOST) [15,16].