All lipid-related phecode associations from the PCSK9, APOB, and LDLR variants were replicated in the Marshfield PMRP, BioVU and/or UK cohorts; however, the non-lipid association of rs6511720 with the phecode “myopia” was not confirmed in any of the replication cohorts (Table 3). The gene discussed is PCSK9; the disease is myopia.