TLR4 and acute myeloid leukemia: Also, a higher expression of TLR4 in AML-M3 cases was observed compared to non-M3 AML patients (the mean values of the delta Ct in AML-M3 vs. non-M3, -3.27±7.85 vs 4.23±0.63, P = 0.0001) (Figure 4) (Table5).