B-ALL involves characteristic chromosomal translocations such as t(12;21) [ETV6-RUNX1], t(1;19) [TCF3-PBX1], t(9;22) [BCR-ABL1] and rearrangements of the MLL locus (Woo et al., 2014). The gene discussed is BCR; the disease is acute lymphoblastic leukemia.