Additionally, the REGN2810 study (Papadopoulos et al., 2016), a phase I multicenter study, assessed REGN2810 (a PD-1 mAb) as a monotherapy and in combination with hfRT, in combination with cyclophosphamide (CTX) or with CTX + hfRT in patients with advanced solid tumors, including cervical cancer. The gene discussed is PDCD1; the disease is cervical carcinoma.